Research: MWM and patients with with knee osteoarthritis

Long term efficacy of mobilisation with movement on pain and functional status in patients with  knee osteoarthritis: a randomised clinical trial

Aishwarya Nigam, Kiran H Satpute and Toby M Hall



Objectives: To evaluate the long term effect of mobilisation with movement on disability, pain and

function in subjects with symptomatic knee osteoarthritis

Design: A randomised controlled trial.

Setting: A general hospital

Subjects: Forty adults with knee osteoarthritis (grade 1–3 Kellgren–Lawrence scale).

Interventions: The experimental group received mobilisation with movement and usual care (exercise

and moist heat) while the control group received usual care alone in six sessions over two weeks.

Main Measures: The primary outcome was the Western Ontario McMaster University Osteoarthritis

index, higher scores indicating greater disability. Pain intensity over 24 hours and during sit to stand

were measured on a 10 centimetre visual analogue scale. Functional outcomes were the timed up and go

test, the 12 step stair test, and knee range of motion. Patient satisfaction was measured on an 11 point

numerical rating scale. Variables were evaluated blind pre- and post intervention, and at three and six

months follow-up.

Results: Thirty five participants completed the study. At each follow-up including six-months, significant

differences were found between groups favouring those receiving mobilisation with movement for all

variables except knee mobility. The primary outcome disability showed a mean difference of 7.4 points

(95% confidence interval, 4.5 to 10.3) at six-months and a mean difference of 13.6 points (95% confidence

interval, 9.3 to 17.9) at three-months follow-up.

Conclusion: In patients with symptomatic knee osteoarthritis, the addition of mobilisation with

movement provided clinically significant improvements in disability, pain, functional activities and patient satisfaction six months later.

Clinical Rehabilitation

© The Author(s) 2020

Article reuse guidelines: DOI: 10.1177/0269215520946932